Tuesday, December 27, 2011

Curly Arrow - Established 18th October 2006

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Merry Christmas and Happy New Year! I Hope that everyone is getting some well-deserved time off. I used to do a yearly post on visitor st...
Monday, November 21, 2011

Let's Talk About TLCs Part 5 - Iodine Stain

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The iodine stain is by far the easiest stain to prepare and use. The classic way is to simply have a chamber with some iodine crystals that ...
9 comments:
Tuesday, November 15, 2011

Reverse Phase Silica - Sort of!

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I'm sure that all the synthetic organic chemists will agree that column chromatography is something we simply couldn't live without....
25 comments:
Monday, April 18, 2011

Triazoles in Peptidomimetic Chemistry

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Self Promotion time! Our review on 1,2,3-Triazoles in Peptidomimetic Chemistry was just published in EuroJOC . Useful stuff if you are worki...
2 comments:
Tuesday, March 08, 2011

The Sand Bath - An Alternative to the Oil Bath

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Yes, I am still alive! I have been out of the lab for a loooong time so the inspiration hasn't been there. However, I am now finding my...
14 comments:
Wednesday, October 27, 2010

Is there a Future for Organic Chemists in the Pharmaceutical Industry outside China and India?

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I have copy/pasted the headline for this post from the editorial in the most recent issue of Organic Process Research and Development . It...
8 comments:
Friday, October 08, 2010

If it works don't mess with it!

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I'm currently in Brussels vistiting a collaborator. The research groups lab is absolutely fascinating and contains several old school m...
4 comments:
Wednesday, September 01, 2010

NMR Impurities Tabulated

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If you didn't already spot this useful paper on NMR impurities you should go get it now. An excellent addition to the classic paper by ...
2 comments:
Friday, July 16, 2010

PhD in Medicinal Chemistry

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Design and synthesis of the first selective ligands for the GPRC6A receptor – a novel human G-protein coupled receptor with unknown physio...
1 comment:
Tuesday, June 22, 2010

Green

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This is what 40 g of the depicted indole looks like after one recrystallisation. It really shouldn't be green but it is very pretty and ...
11 comments: