This blog is devoted to the discussion of all aspects of synthetic organic chemistry and related sciences. Curly Arrow is run by a synthetic organic chemist based in Copenhagen, Denmark. Contributions from readers are always welcome and should be emailed to curlyarrow@gmail.com
Wednesday, October 21, 2009
Butt-in-diol?
Old school 1,4-butynediol. A wondeful and cheap building block. D!
Apologies to RTHL for deleting his/her comment by mistake. Here it is:
"this chemical is crazy hard to dissolve for whatever reason, I tried standard acylation chemistry with this guy and was shocked at how much DCM, Et3N, and eventually 3 hours in, MeCN, i needed to actually get it in solution before i added the acyl chloride"
Old school 1,4-butynediol. A wondeful and cheap building block. D!
I love your blog :o)
ReplyDeleteShort, sharp and to the point. I love it. We have hundreds of these kinds of old school bottles in our cabinets. Remnants of a better time.
ReplyDeleteFantastic chemical, nice crystals and so useful!
ReplyDeleteso boring and linear. You oughta make bis-perchlorate ester of it and then post the pictures of the resulting hole in your bench
ReplyDeleteApologies to RTHL for deleting his/her comment by mistake. Here it is:
ReplyDelete"this chemical is crazy hard to dissolve for whatever reason, I tried standard acylation chemistry with this guy and was shocked at how much DCM, Et3N, and eventually 3 hours in, MeCN, i needed to actually get it in solution before i added the acyl chloride"
D!