Synthetic organic chemists often have to transfer something pyrophoric, toxic, volatile, smelly etc. from a commercially acquired sealed bottle such as a Sigma-Aldrich Sure/Seal bottle using a needle and syringe. Even with great care it has a tendency to drip from the needle tip, which is the last thing you are interested in. Now a Danish team has published a simple DIY solution that should be adapted broadly since it solves the problem and increases lab safety.
Basically they have developed a 3D printed mount for the sealed bottle that makes is easy and safe to remove what you need (using both hands) and the needle tip is contained inside a small airlock during transport to the reaction vessel. I have taken the liberty of inserting a figure from the paper above that describes the set-up nicely. If you use this set-up and remember to always employ Luer locked syringes I believe that most accidents can be eliminated and that we can avoid another Sheri Sangji incident in the future. D!
orcid.org/0000-0003-3926-7047
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2 comments:
I find it incredibly annoying that they employ a straight needle. If the needle is kept in this position, you will always have some drops fall out. Where is their pressure equalization for the pyrophoric reagent? There is an Aldrich technical bulletin for this:
https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Aldrich/Bulletin/al_techbull_al134.pdf?utm_source=redirect&utm_medium=promotional&utm_campaign=insite_al_techbull_al134
To be pedantic, Shari Sangii's accident happened because (IIRC) she pulled out way too much tBuLi for the volume of syringe she selected, and the plunger fell out. This wouldn't have prevented that.
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