Sunday, February 18, 2007
RACIOC 22 Highlights Part I
So I'm finally recovering from the conference followed by a pile of grant proposals and other stuff. Overall the conference was pretty good. The conference was a joint physical organic and organic conference and they attempted making sessions of general interest to everyone which is commendable but it didn't really work for me most of the time. Nevertheless, a lot of very good stuff was presented. One of the highlights was a talk given by Professor Michael Sherburn from the Australian National University (ANU) in Canberra entitled "Everything You Ever Wanted To Know About Synthesis". He's an amazing entertainer. I just wish he would start singing and dancing too. He really reminded me of Frank Sinatra and his chemistry is absolutely brilliant - Diels-Alders all the way. He showed some interesting work using dendralenes (e.g. DOI: 10.1021/ja053772+): Kerrie Austin working for Professor Banwell (also at ANU) gave a good presentation on her work with (-)-Complicatic Acid (see structure below) and (+)-Hirsutic Acid C. I've mentioned this work before and there wasn't much I hadn't seen before. However, I have to show my complete ignorance regarding Mander's reagent. It's quite a useful reagent for doing stuff like this (didn't spot the yield for this reaction though): The conference really turned out to be a useful reagents and techniques conference. Professor Erick Carreira from ETH in Zürich gave an excellent presentation as always. He showed some really interesting work using sulfamic acid as an ammonia equivalent in allylic substitution reactions. He showed a whole bunch of reactions and it looked very convincing indeed. Here's an asymmetric example using one of Ben Feringa's ligands (unoptimised, unpublished etc.):With some development this stuff looks like it may be quite useful. To be continued....D!